Methods of diagnosis of bladder cancer, compositions and...

Details Methods of diagnosis of bladder cancer, compositions and... Methods of diagnosis of bladder cancer, compositions and...

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) C07H 21/04 (2006.01) C07K 14/00 (2006.01) C07K 14/47 (2006.01) G01N 33/574 (2006.01)

Patent

CA 2453098

Described herein are genes whose expression are up-regulated or down-regulated in bladder cancer. Also described are such genes whose expression is further up-regulated or down-regulated in drug-resistant bladder cancer cells. Related methods and compositions that can be used for diagnosis, prognosis, or treatment of bladder cancer are disclosed. Also described herein are methods that can be used to identify modulators of bladder cancer.

L'invention concerne des gènes dont l'expression est régulée positivement ou négativement dans le cancer de la vessie. Elle concerne également des gènes dont l'expression est davantage régulée positivement ou négativement dans des cellules cancéreuses de vessie résistant au médicaments ; des procédés et des compositions associés pouvant servir à diagnostiquer, pronostiquer ou traiter un cancer de la vessie ; ainsi que des procédés pouvant servir à identifier des modulateurs du cancer de la vessie.

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