Methods of diagnosis of prostate cancer, compositions and...

Details Methods of diagnosis of prostate cancer, compositions and... Methods of diagnosis of prostate cancer, compositions and...

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A61K 39/395 (2006.01) A61K 45/08 (2006.01) A61P 35/00 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C12Q 1/02 (2006.01) C12Q 1/68 (2006.01) G01N 33/543 (2006.01) G01N 33/574 (2006.01) G01N 33/58 (2006.01)

Patent

CA 2425569

Described herein are genes whose expression are up-regulated or down-regulated in prostate cancer. Also described are such genes whose expression is further up-regulated or down-regulated in drug-resistant prostate cancer cells. Related methods and compositions that can be used for diagnosis and treatment of prostate cancer are disclosed. Also described herein are methods that can be used to identify modulators of prostate cancer.

L'invention concerne des gènes dont l'expression est régulée positivement ou négativement dans le cancer de la prostate. L'invention concerne aussi des gènes dont l'expression est régulée davantage positivement ou négativement dans des cellules cancéreuses de prostate résistant aux médicaments ; des procédés et des compositions associées pouvant être utilisés dans le diagnostic et le traitement du cancer de la prostate ; ainsi que des procédés pouvant servir à identifier des modulateurs du cancer de la prostate.

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