Methods of diagnostic image analysis using metal complexes...

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A61K 51/04 (2006.01) A61K 49/00 (2006.01) A61K 49/06 (2006.01)

Patent

CA 2229777

The present invention is directed to complexes represented by formula (I), wherein R, R', R1, R'1, R2, R'2, R3, R'3, R4, R'4, R5, R'5, R6, R'6, R7, R'7, R8, R'8, R9, R'9, M, X, Y, Z and n are defined herein for use as contrast agents in diagnostic imaging.

Conjugués biologiques de complexes représentés par la formule (I). Dans cette formule, R, R', R¿1?, R'¿1?, R¿2?, R'¿2?, R¿3?, R'¿3?, R¿4?, R'¿4?, R¿5?, R'¿5?, R¿6?, R'¿6?, R¿7?, R'¿7?, R¿8?, R'¿8?, R¿9?, R'¿9?, M, X, Y, Z et n sont définis de manière à servir d'agents de contraste en imagerie diagnostique.

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