Methods of enhancing chemotherapy with the use of an imidazole

Details Methods of enhancing chemotherapy with the use of an imidazole Methods of enhancing chemotherapy with the use of an imidazole

A - Human Necessities

61

K

A61K 31/4164 (2006.01) A61K 31/337 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2382727

Provided are methods for treating neoplastic cell disorders including cancer by administering a therapeutically effective dose of a compound of Formula (I), derivatives, analogues or salts thereof. Also provided are chemoprotective method utilizing the compound of Formula (I), derivatives, analogues or salts thereof, methods of increasing the bioavailability of a chemotherapeutic agents, as well as methods of preventing the emergence of multi-drug resistant neoplastic cells.

L'invention concerne des procédés permettant de traiter des troubles liés aux cellules néoplasiques, y compris le cancer, par administration d'une dose thérapeutique efficace d'un composé représenté par la formule (I), des dérivés ou des composés analogues ou des sels. L'invention concerne également un procédé de chimiothérapie utilisant le composé représenté par la formule (I), des dérivés, des composés analogues ou des sels. L'invention concerne également des procédés permettant d'augmenter la biodisponibilité d'agents chimiothérapeutiques, ainsi que des procédés permettant de prévenir l'émergence de cellules néoplasiques résistant aux antibiotiques.

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