Methods of enhancing cognitive function using non-peptidic...

Details Methods of enhancing cognitive function using non-peptidic... Methods of enhancing cognitive function using non-peptidic...

A - Human Necessities

61

K

A61K 31/415 (2006.01) A61K 31/166 (2006.01) A61K 31/341 (2006.01) A61K 31/381 (2006.01) A61P 25/28 (2006.01)

Patent

CA 2692775

Disclosed are methods of enhancing cognitive impairment in a patient wherein the cognitive impairment is due to ADDL neurotoxicity. The methods employ non-peptidic compounds having a molecular weight of less than 1000 and which can antagonize against formation of neurotoxic ADDLs from A.beta.1-42 monomers.

L'invention concerne des procédés d'amélioration des troubles cognitifs chez un patient, les troubles cognitifs étant dus à la neurotoxicité de l'ADDL. Les procédés utilisent des composés non peptidiques ayant un poids moléculaire inférieur à 1000 et pouvant contrarier la formation d'ADDL neurotoxiques à partir de monomères Ab1-42.

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