A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/33 (2006.01) A61K 31/00 (2006.01) A61K 31/485 (2006.01) A61K 38/08 (2006.01) A61K 45/06 (2006.01) A61P 25/04 (2006.01) A61P 25/36 (2006.01)
Patent
CA 2168262
A composition, and methods of enhancing the analgesic potency of morphine and other clinically used bimodally-acting opioid agonists or detoxifying and treating an opiate addict comprising the co-administration of a bimodally-acting opioid agonist which activates inhibitory opioid receptor-mediated functions of neurons in the nociceptive (pain) pathways of the nervous system and an excitatory opioid receptor antagonist which selectively excitatory opioid agonists.
Composition et procédés d'amplification de l'efficacité analgésique de la morphine et d'autres agonistes d'opioïdes à action bimodale utilisés cliniquement ou de désintoxication et de traitement d'un individu dépendant d'opiacés, comprenant l'administration conjointe d'un agoniste d'opioïde à action bimodale activant les fonctions inhibitrices, déclenchées par des récepteurs d'opioïdes, de neurones sur les trajets de la douleur du système nerveux et d'un antagoniste de récepteur d'opioïde excitant qui inactive sélectivement des agonistes d'opioïdes excitants
Crain Stanley
Shen Ke-Fei
Albert Einstein College Of Medicine Of Yeshiva University
Ridout & Maybee Llp
LandOfFree
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