A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 33/24 (2006.01) A61K 9/70 (2006.01) A61K 31/28 (2006.01) A61K 33/06 (2006.01) A61K 33/22 (2006.01) A61K 38/40 (2006.01) A61L 26/00 (2006.01)
Patent
CA 2073453
Skin, connective and support tissue repair is enhanced and augmented by administering pharmaceutically acceptable galli- um-containing compounds in amounts sufficient to provide therapeutic levels of elemental gallium. Gallium-containing com- pounds mimic the effects of endogenous growth factors to induce cells within these tissues to produce new matrix by increasing the formation of critical structural matrix proteins responsible for skin, support and connective tissue repair, maintenance and augmentation. Gallium-containing coumpounds are suitable for a variety of applications in wound healing, including dermato- logic and cosmetic skin repair, bone fracture repair and successful bonding of implanted tissue grafts and connective and support tissue prostheses. The unique ability of the gallium-containing compounds to increase new matrix component formation and fa- vorably alter the proliferation of specific cell types needed for tissue repair is separate and distinct from gallium's inhibitory ae- tivity on matrix-resorbing cells such as bone-resorbing osteoclasts.
Bockman Richard
Guidon Peter
Bereskin & Parr
New York Society For The Relief Of The Ruptured And Crippled Maintaining The Hospital For Special Surgery
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