Methods of expressing heterologous protein in plant seeds...

Details Methods of expressing heterologous protein in plant seeds... Methods of expressing heterologous protein in plant seeds...

A - Human Necessities

01

H

A01H 1/00 (2006.01) A01H 5/00 (2006.01) C07H 21/04 (2006.01) C12N 15/11 (2006.01) C12N 15/82 (2006.01) C12N 15/87 (2006.01)

Patent

CA 2551392

The invention is directed to expression of non-plant proteins in rice plants. Expression is optimized by use of a non-rice promoter of a monocot protein gene and its corresponding signal peptide for expression of the non-plant protein in rice plant at high yields. The invention is useful for making human proteins, polypeptides and peptides in rice seeds. The expressed protein product can be isolated from the rice seed for administration to humans or other animals.

La présente invention se rapporte à l'expression de protéines non végétales dans des plants de riz. L'on optimise ladite expression en faisant appel à un promoteur qui n'est pas issu du riz d'un gène d'une protéine de monocotylédone et à son peptide signal correspondant, afin d'exprimer la protéine non végétale dans le plant de riz à des rendements élevés. L'invention peut servir à produire des protéines, des polypeptides et des peptides humains dans les plants de riz. Le produit protéique exprimé peut être isolé de la graine de riz, afin qu'il soit administré à des êtres humains ou à des animaux.

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