Methods of facilitating vascular growth

Details Methods of facilitating vascular growth Methods of facilitating vascular growth

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) A61K 38/02 (2006.01) A61K 38/19 (2006.01) A61K 39/395 (2006.01) A61K 48/00 (2006.01) C07K 16/22 (2006.01)

Patent

CA 2340468

A method of facilitating vascular growth in a subject in need of such treatment comprises inhibiting EMAP II activity in the subject by an amount effective to stimulate vascular growth in the subject (e.g., in the lungs or heart of the subject). Pharmaceutical formulations useful for carrying out such methods (e.g., an antibody that specifically binds to EMAP II in a pharmaceutically acceptable carrier) and screening techniques useful for identifying additional compounds that can be used for carrying out such methods are also disclosed.

L'invention concerne un procédé destiné à faciliter la croissance vasculaire chez un sujet nécessitant un tel traitement, et consistant à inhiber l'activité de EMAP II (polypeptide activant le monocyte endothélial), par administration audit sujet d'une dose efficace, afin de stimuler la croissance vasculaire (par exemple dans les poumons ou le coeur du sujet). L'invention concerne également des formulations pharmaceutiques, utiles dans l'exécution de tels procédés (par exemple un anticorps se liant de manière spécifique à EMAP II et placé dans un support acceptable sur le plan pharmacologique), ainsi que des techniques de criblage, utiles pour identifier des composés additionnels que l'on peut utiliser pour l'exécution desdits procédés.

Affiliated with

Also associated with

Rating

Methods of facilitating vascular growth does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Methods of facilitating vascular growth, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods of facilitating vascular growth will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1850695