A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/506 (2006.01) C12Q 1/68 (2006.01)
Patent
CA 2610157
The invention described herein relates to methods of identifying and treating individuals with protein tyrosine kinase associated disorders that have, or may, become resistant to treatment with a kinase inhibitor such as imatinib due to a gain-of- function mutation in KIT tyrosine kinase.
L'invention porte sur une méthodes d'identification et de traitement d'individus présentant des troubles associés à la tyrosine kinase et qui sont ou peuvent devenir résistants à un traitement par un inhibiteur de la kinase tel que l'imatinib, en raison d'une mutation avec gain de fonction de la tyrosine kinase KIT.
Heinrich Michael C.
Lee Francis Y.
Bristol-Myers Squibb Company
Oregon Health And Science University
Smart & Biggar
The United States Of America As Represented By The Department Of
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