C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/02 (2006.01) G01N 33/50 (2006.01) G01N 33/566 (2006.01) G01N 33/94 (2006.01)
Patent
CA 2413451
Methods for identifying substances that are agonists of GABAB receptors that are heteromers of gb1a and gb2 subunits where the substances are not agonists of GABAB receptors that are heteromers of gb1b and gb2 subunits or gb1c and gb2 subunits are provided. The substances are useful for the treatment of a variety of conditions, e.g., epilepsy and certain pain syndromes.
La présente invention concerne des techniques d'identification de substances qui sont des agonistes des récepteurs GABA¿B? et qui sont des hétéromères des sous unités gb1 et gb2 ou des sous unités gb1c et gb2. Ces substances conviennent pour le traitement d'une variété de pathologies, par exemple l'épilepsie et certains syndromes de la douleur.
Merck Frosst Canada & Co.
Ng Gordon
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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