C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01)
Patent
CA 2597611
The present invention relates to methods of identifying and/or characterizing genes that are modulated during myelination or remyelination, as well as in demyelinating diseases such as in multiple sclerosis. The invention further provides methods of treating diseases related to myelination in a mammal, such as multiple sclerosis, by administering agents that promote remyelination of oligodendrocytes.
La présente invention concerne des méthodes d'identification et/ou de caractérisation de gènes qui sont modulés au cours de la myélinisation ou de la remyélinisation, ainsi que dans des maladies démyélinisantes telles que dans la sclérose en plaques. L'invention concerne également des méthodes de traitement de maladies associées à la myélinisation chez un mammifère, comme la sclérose en plaques, par administration d'agents qui favorisent la remyélinisation d'oligodendrocytes.
Elan Pharmaceuticals Inc.
Smart & Biggar
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