C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/00 (2006.01) C12Q 1/68 (2006.01) G01N 33/50 (2006.01)
Patent
CA 2373550
The invention provides a method of identifying therapeutic compounds in a genetically defined setting. The method consists of contacting a cell indicative of a pathological condition from a diseased individual and a cell from a genetically related normal individual with a plurality of candidate therapeutic compounds under suitable assay conditions, and identifying a compound that preferentially alters a predetermined property of the cell from the diseased individual.
L'invention concerne une méthode permettant d'identifier des composés thérapeutiques dans un contexte génétiquement défini. Cette méthode consiste à mettre en contact une cellule signalant un état pathologique chez un individu malade et une cellule d'un individu bien portant, génétiquement lié à l'individu malade, avec une pluralité de composés thérapeutiques candidats, dans des conditions d'analyse appropriées, puis à identifier un composé qui modifie, de préférence, une propriété prédéterminée de la cellule de l'individu malade.
Gowling Lafleur Henderson Llp
Palsson Bernhard O.
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