C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 5/00 (2006.01) C12N 5/02 (2006.01) A61K 35/12 (2006.01) A01N 65/00 (2006.01) C12N 5/06 (2006.01) C12N 5/08 (2006.01)
Patent
CA 2493871
The invention relates to methods of isolating and implanting mesenchymal stem cells for tissue repair or formation, without prior culture expansion of the mesenchymal stem cells. In particular, the invention relates to methods of isolating mesenchymal stem cells from bone marrow, for repairing or inducing formation of bone, without prior culture expansion of the mesenchymal stem cells. The invention further relates to an isolated, non-culurally expanded human adult mesenchymal stem cell population.
L'invention concerne des procédés servant à isoler et à implanter des cellules souches mésenchymateuses pour la réparation ou le développement tissulaires sans culture préalable démultipliée de ces cellules souches. Elle concerne, en particulier, des procédés servant à isoler ces cellules souches mésenchymateuses de la moelle osseuse afin de réparer ou d'induire le développement de l'os sans multiplication préalable dans une culture de ces cellules souches mésenchymateuses. Elle concerne, de plus, une population de cellules souches mésenchymateuses adultes humaines isolée et non soumise à une multiplication par culture.
Aslan Hadi
Gazit Dan
Gazit Zulma
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
Yissum Research Development Company Of The Hebrew University Of
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