A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/18 (2006.01) A61K 38/19 (2006.01) A61K 47/36 (2006.01) A61P 25/16 (2006.01) A61P 25/28 (2006.01)
Patent
CA 2327208
The present invention provides a method of increasing the volume of distribution of a therapeutic agent in a tissue in a subject during localized delivery comprising administering to the tissue in the subject a therapeutic agent and a facilitating agent, whereby the inclusion of the facilitating agent increases the volume of distribution of the therapeutic agent in the tissue. The invention also provides a method of increasing the pharmacological activity of a therapeutic agent in a tissue in a subject during localized delivery, comprising administering to the tissue in the subject a therapeutic agent and a facilitating agent, whereby the inclusion of the facilitating agent increases the pharmacological activity of the therapeutic agent in the tissue.
Bankiewicz Krys
Hamilton John
Oldfield Edward
Phillips Heidi
Genentech Inc.
Gowling Lafleur Henderson Llp
The Government Of The United States Of America
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