Methods of increasing nitric oxide synthesis

Details Methods of increasing nitric oxide synthesis Methods of increasing nitric oxide synthesis

A - Human Necessities

61

K

A61K 31/445 (2006.01) A61K 31/38 (2006.01) A61K 31/40 (2006.01) A61K 31/4025 (2006.01) A61K 31/4535 (2006.01) A61K 31/55 (2006.01)

Patent

CA 2255792

The current invention provides methods for increasing the concentration of nitric oxide (NO) in vascular endothelial cells, comprising administering a compound of formula (I), wherein: R is hydrogen, -OH, -O(C1-C4 alkyl), -OCO(C1- C4 alkyl), or -OCOAr where Ar is a phenyl or optionally substituted phenyl; R1 is R, -C1, or -F; R2 is 1-pyrrolidinyl, 1-piperidinyl, or 1- hexamethyleneimino; or a pharmaceutically acceptable salt or solvate thereof.

L'invention concerne des procédés d'augmentation de la concentration de monoxyde d'azote (NO) dans les cellules de l'endothélium vasculaire, qui consistent à administrer un composé de formule (I), un sel ou un solvate de celui-ci. Dans ladite formule (I), R représente hydrogène, -OH, -O(C¿1?-C¿4?alkyle), -OCO(C¿1?-C¿4?alkyle), ou -OCOAr où Ar représente phényle ou phényle éventuellement substitué; R¿1? représente R, -Cl, ou -F; R¿2? représente 1-pyrrolidinyle, 1-pipéridinyle ou 1-hexaméthylèneimino.

Affiliated with

Also associated with

Rating

Methods of increasing nitric oxide synthesis does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Methods of increasing nitric oxide synthesis, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods of increasing nitric oxide synthesis will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-2041573