A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/445 (2006.01) A61K 31/38 (2006.01) A61K 31/40 (2006.01) A61K 31/4025 (2006.01) A61K 31/4535 (2006.01) A61K 31/55 (2006.01)
Patent
CA 2138490
A method of increasing thrombomodulin expression comprising administering to a human in need of treatment an effective amount of a compound having the formula Image (I) wherein R1 and R3 are independently hydrogen, Image Image -CH3, , or , wherein Ar is optionally substituted phenyl; R2 is selected from the group consisting of pyrrolidino, hexamethyleneamino, and piperidino; or a pharmaceutically acceptable salt of solvate thereof. wherein R1 and R3 are independently hydrogen, -CH3, Image , or Image , wherein Ar is optionally substituted phenyl; R2 is selected from the group consisting of pyrrolidino, hexamethyleneimino, and piperidino; and pharmaceutically acceptable salts and solvates thereof. Also encompassed by the invention is a method of inhibiting a thrombotic disorder or event which includes administering to a human in need thereof an effective amount of a compound of formula 1. Also encompassed by the invention is a method of increasing Protein C activation rate which includes the administration of a compound of formula 1.
Calnek David Scott
Grinnell Brian William
Eli Lilly And Company
Gowling Lafleur Henderson Llp
LandOfFree
Methods of increasing thrombomodulin expression does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Methods of increasing thrombomodulin expression, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods of increasing thrombomodulin expression will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1349620