Methods of inducing hair growth and coloration

A - Human Necessities – 61 – K

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A61K 38/18 (2006.01) A61K 38/12 (2006.01) A61Q 7/00 (2006.01) C07K 7/64 (2006.01) C07K 14/475 (2006.01) C12N 15/11 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2320483

Methods to control, or manipulate, melanocyte and keratinocyte cell death are disclosed. In particular, a method of preventing epidermal melanocyte cell loss due to injury in a vertebrate is disclosed. Also disclosed is a method of inducing hair growth in a vertebrate, a method of inducing hair color in a vertebrate, a method of inducing skin color in a vertebrate, a method of treating baldness in an individual and a method of treating alopecia areata in an individual.

Procédés permettant de réguler, ou de manipuler, l'apoptose des mélanocytes et des kératinocytes, et en particulier procédé permettant d'empêcher la perte cellulaire de mélanocytes épidermiques due à une lésion chez un vertébré. Un procédé d'induction de la croissance capillaire, de la coloration capillaire, et de la coloration de la peau chez un vertébré, et un procédé de traitement de la calvitie ainsi que de la pelade chez un sujet sont également décrits.

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