Methods of inhibiting bacterial virulence and compounds...

C - Chemistry – Metallurgy – 07 – C

Patent

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Details

C07C 311/47 (2006.01) A01N 41/06 (2006.01) A01N 43/40 (2006.01) A01N 47/30 (2006.01) A61K 31/17 (2006.01) A61K 31/18 (2006.01) A61K 31/4406 (2006.01) A61K 31/63 (2006.01) A61K 31/635 (2006.01) A61K 47/48 (2006.01) A61P 31/04 (2006.01)

Patent

CA 2702992

The present invention relates to compounds and methods for the treatment of bacterial infections. Because their mechanism of action does not involve killing of bacteria or inhibiting their growth, the potential for these compounds to induce drug resistance in bacteria is minimized. Through inhibiting bacterial virulence, the present invention provides a novel means of treating bacterial infections.

La présente invention porte sur des composés et des procédés pour le traitement d'infections bactériennes. En raison du fait que leur mécanisme d'action ne met pas en jeu la destruction de bactéries ou l'inhibition de leur croissance, le potentiel pour ces composés à induire une résistance à un médicament dans des bactéries est rendu minimal. Par l'inhibition de la virulence bactérienne, la présente invention porte sur de nouveaux moyens de traitement d'infections bactériennes.

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