Methods of inhibiting btk and syk protein kinases

Details Methods of inhibiting btk and syk protein kinases Methods of inhibiting btk and syk protein kinases

A - Human Necessities

61

K

A61K 31/502 (2006.01) A61P 11/06 (2006.01) A61P 19/02 (2006.01) A61P 25/00 (2006.01)

Patent

CA 2645583

Methods of inhibiting a tyrosine kinase wherein said tyrosine kinase is BTK or SYK comprising administering to a patient in need thereof a therapeutically effective amount of a compound according to formula (I) as described in claim 1 are disclosed. The compounds are useful for treating auto-immune and inflammatory diseases.

la présente invention concerne des procédés permettant d'inhiber une tyrosine kinase, ladite tyrosine kinase étant la protéine BTK ou la protéine SYK. Les procédés consistent à administrer à un patient la nécessitant une quantité thérapeutiquement efficace d'un composé répondant à la formule (I), tel qu'il est décrit dans la revendication 1. Les composés sont utiles pour le traitement de maladies auto-immunes et inflammatoires.

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