Methods of inhibiting calcineurin with apoe analogs

Details Methods of inhibiting calcineurin with apoe analogs Methods of inhibiting calcineurin with apoe analogs

A - Human Necessities

61

K

A61K 38/10 (2006.01) A61K 38/08 (2006.01) A61K 38/16 (2006.01) A61P 25/00 (2006.01)

Patent

CA 2692847

The present invention provides a method of modulating calcineurin activity in a cell by contacting the cell with at least one ApoE analog. Methods of treating various disorders associated with calcineurin activity using one or more ApoE analogs are also disclosed. In particular, the present invention provides a method of reducing demyelinaton and promoting remyelination in a subject. Methods of treating spinal cord or nerve injury in a subject are also described.

La présente invention propose un procédé pour moduler l'activité de la calcineurine dans une cellule en mettant en contact la cellule avec au moins un analogue d'APOE. Des procédés de traitement de divers troubles associés à une activité de la calcineurine utilisant un ou plusieurs analogues d'APOE sont également révélés. En particulier, la présente invention propose un procédé de réduction de la démyélination et de favorisation de la remyélination chez un sujet. Des procédés de traitement d'une lésion de la moelle épinière ou des nerfs rachidiens chez un sujet sont également décrits.

Affiliated with

Also associated with

Rating

Methods of inhibiting calcineurin with apoe analogs does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Methods of inhibiting calcineurin with apoe analogs, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods of inhibiting calcineurin with apoe analogs will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1959837