A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/445 (2006.01) A61K 31/38 (2006.01) A61K 31/381 (2006.01) A61K 31/40 (2006.01) A61K 31/4025 (2006.01) A61K 31/4535 (2006.01)
Patent
CA 2212339
A method of inhibiting cell-cell adhesion comprising administering to a human in need thereof an effective amount of a compound having formula (I), wherein R1 and R3 are independently hydrogen, -CH3, (a), or (b), wherein Ar is optionally substituted phenyl; R2 is selected from the group consisting of pyrrolidine, hexamethyleneimino, and piperidino; or a pharmaceutically acceptable salt of solvate thereof.
On décrit un procédé d'inhibition de l'adhésion cellule/cellule, qui consiste à administrer à un humain nécessitant un tel traitement une dose efficace d'un composé de la formule (I), ou d'un sel ou d'un solvate de celui-ci, acceptable sur le plan pharmacologique. Dans cette formule, R?1¿ et R?3¿ représentent indépendamment hydrogène, -CH¿3?, (a), ou (b), dans lequel Ar représente phényle éventuellement substitué; R?2¿ est choisi dans le groupe comprenant pyrrolidine, hexaméthylène-imino et pipéridino.
Eli Lilly And Company
Gowling Lafleur Henderson Llp
LandOfFree
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