Methods of inhibiting cell death or inflammation in a mammal

Details Methods of inhibiting cell death or inflammation in a mammal Methods of inhibiting cell death or inflammation in a mammal

A - Human Necessities

61

K

A61K 38/17 (2006.01)

Patent

CA 2583004

In one aspect the present invention provides methods for inhibiting cell death or inflammation in a mammal, wherein the methods each include the step of administering to a mammal a Bcl protein in an amount sufficient to inhibit cell death or inflammation in the mammal. The invention also provides methods for identifying a Bcl protein that inhibits cell death or inflammation when administered to a mammal.

Dans un aspect de l'invention, des méthodes sont destinées à inhiber une mort cellulaire ou une inflammation chez un mammifère. Ces méthodes peuvent comprendre chacune une étape d'administration, à un mammifère, d'une protéine Bcl, dans une quantité suffisante pour inhiber la mort cellulaire ou l'inflammation chez l'animal. L'invention concerne également des méthodes pour identifier une protéine Bcl inhibant une mort cellulaire ou une inflammation, lorsque cette protéine est administrée à un mammifère.

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