Methods of inhibiting metastasis

Details Methods of inhibiting metastasis Methods of inhibiting metastasis

C - Chemistry, Metallurgy

07

K

C07K 16/28 (2006.01) A61P 35/04 (2006.01) C07K 14/715 (2006.01) C07K 16/24 (2006.01) G01N 33/50 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2389979

Methods of inhibiting metastasis or maintenance of various cancers are provided, the method comprising blocking signaling of a chemokine receptor on the cell. In particular, the method makes use of fact that certain trafficking of cancers depend upon identified proteins, which serve as markers. Additional methods of screening are also provided.

L'invention concerne des procédés d'inhibition de métastases ou de traitement d'entretien de divers cancers. En particulier, le procédé utilise le fait que certaines interactions, dans les cancers, dépendent de protéines identifiées qui servent de marqueurs. L'invention concerne aussi des procédés supplémentaires de criblage.

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