A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/45 (2006.01) A61K 31/352 (2006.01) A61K 31/496 (2006.01) A61P 21/06 (2006.01) G01N 33/50 (2006.01)
Patent
CA 2378982
The present invention provides a method for inhibiting atrophy in muscle cells. It further provides a method for inhibiting skeletal muscle atrophy or causing skeletal muscle hypertrophy in vertebrate animals. It also provides a method of identifying agents, genes and gene products that may be used to reduce proteolysis or increase protein synthesis in muscle cells.
L'invention concerne un procédé permettant d'inhiber l'amyotrophie dans les cellules musculaires. L'invention concerne également un procédé permettant d'inhiber l'atrophie du muscle squelettique ou de développer une hypertrophie du muscle squelettique chez les vertébrés. L'invention concerne également un procédé d'identification d'agents, de gènes et de produits génétiques pouvant être utilisés pour réduire la protéolyse ou pour augmenter la protéogenèse dans les cellules musculaires.
Glass David J.
Rommel Christian
Yancopoulos George D.
Osler Hoskin & Harcourt Llp
Regeneron Pharmaceuticals Inc.
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