Methods of inhibiting platelet activation with selective...

A - Human Necessities – 61 – P

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A61P 9/00 (2006.01) A61K 31/00 (2006.01) A61K 31/135 (2006.01) A61K 31/138 (2006.01) A61K 31/15 (2006.01) A61K 31/343 (2006.01) A61K 31/4525 (2006.01)

Patent

CA 2375219

The present invention pertains to methods for reducing the platelet activation state in an individual comprising administering a selective serotonin reuptake inhibitor (SSRI). The platelet activation state is reduced upon administering a SSRI, as measured by one or more platelet activation markers. The invention also relates to methods for treating or preventing an individual at risk for a vascular event, disease or disorder by administering a SSRI.

L'invention concerne des procédés permettant de réduire l'activation plaquettaire qui consistent à administrer au sujet un inhibiteur sélectif de recaptage de la sérotonine, et la réduction intervient comme en témoigne la mesure d'un ou plusieurs marqueurs d'activation plaquettaire. L'invention concerne également des procédés relatifs au traitement ou à la prévention du risque d'accident, de maladie ou de trouble vasculaire par l'administration de ce type d'inhibiteur.

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