A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/38 (2006.01) A61K 31/381 (2006.01) A61K 31/40 (2006.01) A61K 31/445 (2006.01) A61K 31/55 (2006.01)
Patent
CA 2198122
A method of inhibiting viral replication comprising administering to a human in need thereof an effective amount of a compound having formula (I), wherein R1 and R3 are independently hydrogen, -CH3, (a), or (b), wherein Ar is optionally substituted phenyl; R2 is selected from the group consisting of pyrrolidine, hexamethyleneimino, and piperidino; or a pharmaceutically acceptable salt or solvate thereof.
L'invention concerne un procédé pour inhiber la réplication virale consistant à administrer à un être humain à traiter, une dose efficace d'un composé de la formule (I). Dans cette formule, R?1¿ et R?3¿ représentent indépendamment hydrogène, un groupe -CH¿3?, (a) ou (b), où Ar est un phényle éventuellement substitué; R?2¿ est choisi dans le groupe constitué de pyrrolidine, hexaméthylèneimino et pipéridino. L'invention concerne également un sel ou solvate de ces composés acceptable sur le plan pharmaceutique.
Glasebrook Andrew Lawrence
Phillips David Lynn
Eli Lilly And Company
Gowling Lafleur Henderson Llp
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