A - Human Necessities – 61 – L
Patent
A - Human Necessities
61
L
A61L 31/04 (2006.01) A61F 2/06 (2006.01) A61L 31/10 (2006.01) A61L 31/16 (2006.01) A61L 31/18 (2006.01)
Patent
CA 2636296
A bioabsorbable drug delivery device and various methods of making the same. The devices are preferably formed from bioabsorbable materials using low temperature fabrication processes, whereby drugs or other bio-active agents are incorporated into or onto the device and degradation of the drugs or other agents during processing is minimized. The method includes the steps of preparing a solution of at least one bioabsorbable polymer with a solvent and pouring the solution into a mold. The solvent is then evaporated in a nitrogen environment and the solution is converted into a film. The film is then removed from the mold and residual solvent is removed from the film. The film is then cut into strips and stored in an inert environment.
L'invention concerne un dispositif d'administration de médicament bioabsorbable et divers procédés de fabrication correspondants. Ces dispositifs sont, de préférence, formés à partir de matières bioabsorbables au moyen de processus de fabrication basse température, les médicaments ou autres agents bio-actifs étant incorporés dans ou placé sur le dispositif, la dégradation des médicaments ou des autres agents étant minimisée durant le traitement. Le procédé comprend les étapes consistant à préparer une solution d'au moins un polymère bioabsorbable avec un solvant et à déverser la solution dans un moule. Le solvant est ensuite évaporé dans un environnement d'azote et la solution convertie en un film. Ce film est ensuite retiré du moule et le solvant résiduel retiré du film. Le film est ensuite coupé en bandes et stocké dans un environnement inerte.
Dave Vipul Bhupendra
Kataria Ram L.
Zhang Qiang
Cordis Corporation
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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