Methods of making biocomposite medical constructs and...

A - Human Necessities – 61 – L

Patent

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A61L 27/24 (2006.01) A61L 27/54 (2006.01)

Patent

CA 2740008

The disclosure describes methods of making collagen based biocomposite constructs and related devices. The methods include: (a) winding at least one collagen fiber a number of revolutions about a length of a support member having a long axis, the winding having at least one defined pitch and/or fiber angle relative to the long axis of the support member to form an elongate construct; and (b) applying a fluid polymeric material, such as, for example, an acrylate emulsion and/or other thermoplastic material, onto the collagen fiber during the winding step. Optionally, the fluid polymeric material can include antibiotics and/or other therapeutic agents for additional function/utility.

La présente invention concerne des procédés de fabrication de constructions biocomposites à base de collagène et des dispositifs associés. Les procédés comprennent : (a) l'enroulement d'au moins une fibre de collagène d'une pluralité de tours autour d'une longueur d'un élément de support ayant un grand axe, l'enroulement ayant au moins un pas et/ou un angle de fibre défini par rapport au grand axe de l'élément de support de manière à former une construction allongée ; et (b) l'application d'un matériau polymère fluide, tel que, par exemple, une émulsion d'acrylate et/ou un autre matériau thermoplastique, sur la fibre de collagène pendant l'étape d'enroulement. Facultativement, le matériau polymère fluide peut comprendre des antibiotiques et/ou d'autres agents thérapeutiques pour fonction/utilité additionnelle.

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