Methods of making pancreatic islet cells

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 5/00 (2006.01) C12N 5/02 (2006.01) A61K 35/12 (2006.01) C12N 5/06 (2006.01)

Patent

CA 2375509

The invention features methods of promoting dedifferentiation of pancreatic cells, methods of obtaining pancreatic islet cells from the dedifferentiated pancreatic cells, and methods of treating a subject having a disorder characterized by insufficient pancreatic islet function by administering pancreatic islet cells obtained by these methods.

Cette invention concerne des procédés favorisant la différenciation des cellules pancréatiques, des procédés d'obtention d'îlots de Langerhans à partir de cellules pancréatiques différentiées et des méthodes de traitement d'un sujet souffrant d'une insuffisance de la fonction des îlots de Langerhans par administration de cellules d'îlot de Langerhans obtenues par lesdits procédés.

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