C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 487/04 (2006.01) A61K 31/53 (2006.01) C07K 5/062 (2006.01) C12N 9/16 (2006.01)
Patent
CA 2598270
The present invention relates to methods of modulating the pharmacokinetic and/or pharmacodynamic properties of a compound by attaching at least one functional unit or group to the compound, thereby improving its non-specific binding characteristics and/or pharmacokinetic properties. Compounds comprising at least one functional residue are provided, as are pharmaceutical compositions comprising said compounds.
La présente invention a trait à des procédés de modulation des propriétés pharmacocinétiques et/ou pharmacodynamiques d'un composé par la liaison d'au moins un motif ou groupe fonctionnel au composé, améliorant ainsi ses caractéristiques de liaison non spécifiques et/ou ses propriétés pharmacocinétiques. L'invention a trait à des composés comportant au moins un résidu fonctionnel et à des compositions pharmaceutiques comportant lesdits composés.
Campbell Stewart
Duffy David
Grogan Michael
Kates Steven
Ostuni Emanuele
Smart & Biggar
Surface Logix Inc.
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