A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/00 (2006.01) A61K 9/18 (2006.01) A61K 9/51 (2006.01)
Patent
CA 2563371
The present invention relates to the use of calcium phosphate particles in formulation with allergens for allergic desensitization. Particularly, the invention relates to novel calcium phosphate core particles, particularly nano- and micron-sized particles, as allergen adjuvants and in compositions for inducing allergic desensitization. Methods of making such particles and to methods of inducing a specific immune response using the particles of this invention are also provided. Optionally a surface modifying agent such as cellobiose or polyethylene glycol (PEG) may be used.
La présente invention concerne l'utilisation de particules de phosphate de calcium dans une préparation contenant des allergènes destinée à la désensibilisation allergique. L'invention concerne plus particulièrement de nouvelles particules dont le noyau renferme du phosphate de calcium et plus précisément des nano- et micro-particules, utilisées comme adjuvants d'allergènes et dans des compositions destinées à induire une désensibilisation allergique. L'invention concerne également des procédés de fabrication de ces particules ainsi que des procédés d'induction d'une réponse immunitaire spécifique, utilisant les particules de la présente invention.
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Biosante Pharmaceuticals Inc.
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