Methods of modifying amyloid .beta. oligomers using...

Details Methods of modifying amyloid .beta. oligomers using... Methods of modifying amyloid .beta. oligomers using...

A - Human Necessities

61

K

A61K 31/381 (2006.01) A61K 31/047 (2006.01) A61K 31/12 (2006.01) A61K 31/166 (2006.01) A61K 31/18 (2006.01) A61K 31/415 (2006.01) A61P 25/28 (2006.01)

Patent

CA 2692773

Disclosed are methods of inhibiting, regulating, and/or modulating the formation of soluble, globular, non-fibrillar, neurotoxic amyloid .beta.1-42 oligomers from amyloid .beta.1-42 monomers. Also disclosed are methods of treating a patient suffering from diseases associated with the formation of soluble, globular, non-fibrillar, neurotoxic amyloid .beta.1-42 oligomers.

L'invention concerne des procédés d'inhibition, de régulation, et/ou de modulation de la formation d'oligomères amyloïdes ß1-42 solubles, globulaires, non fibrillaires, neurotoxiques à partir de monomères amyloïdes ß1-42. Des procédés de traitement d'un patient souffrant de maladies associées à la formation d'oligomères amyloïdesbß1-42 solubles, globulaires, non fibrillaires, neurotoxiques sont également décrits.

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