Methods of modulating apoptosis by administration of relaxin...

A - Human Necessities – 61 – K

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A61K 38/17 (2006.01) A01N 63/00 (2006.01) A61K 38/22 (2006.01) C07H 21/04 (2006.01) C07K 14/64 (2006.01) C12N 15/63 (2006.01)

Patent

CA 2425712

The present invention relates to the discovery that relaxin is associated with the development or maturation of body tissues. Knockouts of the gene encoding relaxin result in various abnormalities in the development of various tissues. The present invention provides methods of modulating apoptosis by administering a relaxin agonist or antagonist to a subject.

Cette invention concerne la découverte selon laquelle la relaxine est associée au développement ou à la maturation des tissus de l'organisme. La rupture du gène codant la relaxine entraîne de nombreux dysfonctionnements dans le développement de divers tissus. L'invention concerne des méthodes de modulation de l'apoptose par l'administration d'un agoniste ou d'un antagoniste de la relaxine à un sujet.

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