Methods of modulating c-kit tyrosine kinase function with...

A - Human Necessities – 61 – K

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A61K 31/40 (2006.01) A61K 31/00 (2006.01) A61K 31/404 (2006.01) A61P 11/06 (2006.01) A61P 35/00 (2006.01) A61P 37/08 (2006.01)

Patent

CA 2395461

The present invention concerns compounds and their use to inhibit the activity of a receptor tyrosine kinase. The invention is preferably used to treat cell proliferative disorders such as cancers characterized by over-activity or inappropriate activity c-kit kinase.

L'invention concerne des composés et leur utilisation pour inhiber l'activité d'une kinase tyrosine réceptrice. L'invention s'utilise de préférence pour traiter des troubles dus à la prolifération cellulaire tels que des cancers, caractérisés par une suractivité ou une activité inappropriée de la kinase de type c-kit.

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