Methods of modulating cell proliferation through telomerase...

A - Human Necessities – 61 – K

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

A61K 48/00 (2006.01) A61K 31/70 (2006.01) A61K 38/00 (2006.01) A61K 38/45 (2006.01) A61K 45/00 (2006.01) C12Q 1/48 (2006.01) C12Q 1/68 (2006.01) G01N 33/573 (2006.01) C12N 5/06 (2006.01) C12N 5/08 (2006.01)

Patent

CA 2245462

Method and compositions are provided for the determination of telomere length and telomerase activity, as well as the ability to inhibit telomerase activity in the treatment of proliferative diseases. Particularly, primers are elongated under conditions which minimize interference from other genomic sequences, so as to obtain accurate determinations of telomeric length or telomerase activity. In addition, compositions are provided for intracellular inhibition of telomerase activity and means are shown for slowing the loss of telomeric repeats in aging cells.

Méthode et compositions servant à déterminer la longueur des télomères et l'activité des télomérases, ainsi qu'à inhiber l'activité des télomérases dans le traitement de maladies à évolution chronique. En particulier, des amorces sont allongées dans des conditions permettant de réduire l'interférence avec d'autres séquences génomiques, afin d'obtenir des déterminations précises de la longueur des télomères ou de l'activité des télomérases. De plus, des compositions sont fournies pour l'inhibition intracellulaire de l'activité des télomérases, et des moyens sont décrits pour ralentir la perte de nouveaux télomères dans les cellules vieillissantes.

LandOfFree

Say what you really think

Search LandOfFree.com for Canadian inventors and patents. Rate them and share your experience with other people.

Rating

Methods of modulating cell proliferation through telomerase... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Methods of modulating cell proliferation through telomerase..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods of modulating cell proliferation through telomerase... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFCA-PAI-O-1951508

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.