Methods of modulating il-22 and il-17

A - Human Necessities – 61 – K

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A61K 39/395 (2006.01) A61K 38/20 (2006.01) C07K 16/24 (2006.01)

Patent

CA 2652924

The present application provides methods of modulating immune responses by using IL-22 in combination with at least one of IL-17A, IL-17F, or IL-23 or by using an IL-22 antagonist, such as an antibody or a soluble receptor or a binding protein, in combination with an antagonist of at least one of IL-17A, IL-17F, or IL-23

La présente demande de brevet concerne des procédés de modulation de réponses immunes à l'aide de l'IL-22 combinée aux cytokines IL-17A, IL-17F, et/ou IL-23, ou à l'aide d'un antagoniste de l'IL-22, tel qu'un anticorps ou un récepteur soluble ou encore une protéine de liaison, combiné à un antagoniste des cytokines IL-17A, IL-17F, et/ou IL-23.

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