Methods of modulating il-23 activity; related reagents

Details Methods of modulating il-23 activity; related reagents Methods of modulating il-23 activity; related reagents

A - Human Necessities

61

K

A61K 38/20 (2006.01) A61K 31/7088 (2006.01) A61K 38/17 (2006.01) A61K 39/395 (2006.01) A61P 31/12 (2006.01)

Patent

CA 2556425

Provided are methods of modulating cytokine activity, namely of IL-23, e.g., for the purpose of treating viral infections. Also provided is a method of diagnosing a viral infection based of the detection of p19, IL-23 or IL-23R; or of a nucleic acid encoding p19 or IL-23R as well as a kit for performing the said method of diagnosing.

L'invention concerne des procédés pour moduler l'activité de la cytokine, notamment l'IL-23, par exemple pour traiter les infections virales. L'invention concerne également un procédé pour diagnostiquer une infection virale, fondé sur la détection de p19, IL-23 ou IL-23R. L'invention concerne également un acide nucléique codant la p19 ou l'IL-23R ainsi qu'un kit permettant d'effectuer ledit procédé de diagnostic.

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