Methods of modulating inflammatory cytokines in the cns...

Details Methods of modulating inflammatory cytokines in the cns... Methods of modulating inflammatory cytokines in the cns...

A - Human Necessities

61

K

A61K 38/19 (2006.01) A61K 38/18 (2006.01)

Patent

CA 2185724

Methods for modulating the expression of inflammatory cytokines in the central nervons system comprising administering an effective amount of TGF-.beta. are disclosed. The mothods include suppressing pro-inflammatory cytokines in the central nervous system by administering an effective amount the TGF-.beta. and inducing anti-inflammatory cytokines in the central nervous system by administering an effective amount of TGF-.beta..

L'invention concerne des procédés de modulation de l'expression de cytokines inflammatoires dans le système nerveux central qui consistent à administrer une quantité efficace de TGF-.beta.. Ces procédés comprennent la suppression de cytokines pro-inflammatoires dans le système nerveux central par l'administration d'une quantité efficace de TGF-.beta., et par l'induction de cytokines anti-inflammtoires dans le système nerveux central par l'administration d'une quantité efficace de TGF-.beta..

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