Methods of modulating p33ing1 mediated apoptosis

C - Chemistry – Metallurgy – 12 – N

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C12N 15/12 (2006.01) A61K 38/17 (2006.01) A61K 48/00 (2006.01) C07K 14/47 (2006.01) G01N 33/53 (2006.01) G01N 33/68 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2284730

The invention provides novel methods for modulating apoptosis in eukaryotic cells using peptides and proteins derived from p33ING1 or oligonucleotides derived from the ING1 gene. The invention also provides method of determining the apoptotic characteristic of a eukaryotic cell.

L'invention concerne de nouveaux procédés servant moduler l'apoptose dans des cellules eucaryotes au moyen de peptides et de protéines dérivées de p33<ING1> ou d'oligonucléotides dérivés du gène ING1. Elle concerne également un procédé permettant de déterminer la caractéristique d'apoptose d'une cellule eucaryote.

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