A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/19 (2006.01) A61K 31/7088 (2006.01) A61K 38/17 (2006.01) A61K 39/395 (2006.01) A61P 35/00 (2006.01) A61P 37/00 (2006.01) C07K 14/52 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2396114
Manipulation of the EphB6 receptor and its active Eph partners allow for regulation of T cell responses, including TCR signalling, T cell proliferation, and induction of T cell death. Methods of modulating EphB6 are described as well as various therapeutic applications.
L'invention concerne des manipulations du récepteur EphB6 et de ses partenaires Eph permettant de réguler les réponses des lymphocytes T, la signalisation TCR, la prolifération des lymphocytes T, ainsi que l'induction de la mort du lymphocyte T. Outre les procédés de modulation du récepteur EphB6, l'invention concerne également diverses applications thérapeutiques.
Freywald Andrew
Grunberger Thomas
Grunebaum Eyal
Roifman Chaim M.
Sharfe Nigel
Smart & Biggar
The Hospital For Sick Children
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