Methods of monitoring conditions by sequence analysis

Details Methods of monitoring conditions by sequence analysis Methods of monitoring conditions by sequence analysis

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) G06F 19/24 (2011.01) C40B 30/02 (2006.01)

Patent

CA 2742380

There is a need for improved methods for determining the diagnosis and prognosis of patients with conditions, including autoimmune disease and cancer. Provided herein are methods for using DNA sequencing to identify personalized biomarkers in patients with autoimmune disease and other conditions. Identified biomarkers can be used to determine the disease state for a subject with an autoimmune disease or other condition.

Selon l'invention, il existe un besoin pour des procédés améliorés pour déterminer le diagnostic et le pronostic de patients avec des maladies, comprenant les maladies auto-immunes et le cancer. L'invention porte sur des procédés pour utiliser le séquençage de l'ADN pour identifier des biomarqueurs personnalisés chez des patients avec une maladie auto-immune et autres maladies. Des biomarqueurs identifiés peuvent être utilisés pour déterminer l'état de maladie pour un sujet ayant une maladie auto-immune ou une autre maladie.

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