Methods of predicting a benefit of antioxidant therapy for...

C - Chemistry – Metallurgy – 07 – H

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C07H 21/04 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2550962

A method of determining a potential of a diabetic patient to benefit from anti oxidant therapy for treatment of a vascular complication, the method comprising determining a haptoglobin phenotype of the diabetic patient and thereby determining the potential of the diabetic patient to benefit from said anti oxidant therapy, whereby a patient having a haptoglobin 2-2 phenotype benefits from anti oxidant therapy more than a patient having a haptoglobin 1- 2 phenotype or a patient having a haptoglobin 1-1 phenotype.

L'invention porte sur une méthode permettant de déterminer le bénéfice potentiel d'une thérapie antioxydante de traitement de complications cardio-vasculaires. Ladite méthode consiste à déterminer le phénotype d'haptoglobine du patient diabétique, et par-là, le bénéfice potentiel d'une telle thérapie. Un patient présentant un phénotype d'haptoglobine 2-2 bénéficiera plus de ladite thérapie qu'un patient présentant un phénotype d'haptoglobine 1-2 ou qu'un patient présentant un phénotype d'haptoglobine 1-1.

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