Methods of predicting cancer lethality using replikin counts

G - Physics – 01 – N

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G01N 33/48 (2006.01) A61K 39/00 (2006.01) A61P 35/00 (2006.01) A61P 35/04 (2006.01) A61P 37/04 (2006.01) G01N 33/68 (2006.01) C07K 16/18 (2006.01) C12N 15/11 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2733461

The present invention provides methods of predicting the relative growth rate, replication rate, or lethality of a first malignancy as compared to another malignancy or as compared to a plurality of malignancies, including methods of predicting the relative growth rate, replication rate, or relative lethality of a primary malignancy as compared to a metastatic malignancy, including comparing the concentration of Replikin sequences in the first malignancy with the concentration of Replikin sequences in another malignancy or malignancies and further provides Replikin peptides and Replikin Peak Genes identified within a malignancy for diagnostic, therapeutic, preventive, and predictive purposes.

La présente invention concerne des procédés de prédiction du taux de croissance relatif, du taux de réplication ou de la létalité dune première tumeur par rapport à une autre tumeur ou par rapport à une pluralité de tumeurs, comprenant des procédés de prédiction du taux de croissance relatif, du taux de réplication ou de la létalité relative dune tumeur primaire par rapport à une tumeur métastasique, comprenant la comparaison de la concentration de séquences de Replikin dans la première tumeur à la concentration de séquences de Replikin dans une autre tumeur ou dautres tumeurs et concerne en outre des peptides de Replikin et des gènes de Replikin maximal identifiés dans une tumeur pour des applications diagnostiques, thérapeutiques, préventives et prédictives.

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