Methods of predicting distant metastasis of lymph...

C - Chemistry – Metallurgy – 12 – Q

Patent

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C12Q 1/68 (2006.01) C07H 21/00 (2006.01) C40B 40/06 (2006.01) C40B 40/10 (2006.01) G01N 33/574 (2006.01)

Patent

CA 2662501

The present invention provides a method for predicting distant metastasis of lymph node negative primary breast cancer by obtaining breast cancer cells; isolating nucleic acid and/or protein from the cells; and analyzing the nucleic acid and/or protein to determine the presence, expression level or status of a Biomarker selected from the pathways in Table 2.

L'invention concerne un procédé destiné à prédire une métastase distante du cancer du sein primaire négatif du ganglion lymphatique par obtention de cellules du cancer du sein; par isolation d'acides nucléiques et/ou de protéines de ces cellules; et par analyse des acides nucléiques et/ou des protéines afin de déterminer la présence, le niveau ou l'état d'expression d'un biomarqueur sélectionné dans les trajets du Tableau 2.

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