Methods of predicting mortality risk by determining telomere...

Details Methods of predicting mortality risk by determining telomere... Methods of predicting mortality risk by determining telomere...

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) C12P 19/34 (2006.01) G01N 1/00 (2006.01)

Patent

CA 2513747

The present invention provides for methods of determining telomere length of an organism and correlating the measured telomere length with mortality risk associated with telomere length in a population. The presence of shorter telomeres is associated with an increased mortality rate and increased susceptibility to certain types of diseases for an individual member of a human population.

La présente invention concerne des procédés qui permettent de mesurer la longueur des télomères d'un organisme et d'établir une corrélation entre la longueur de télomère mesurée et un risque de mortalité associé à une longueur de télomère dans une population. La présence de télomères plus courts chez un membre individuel d'une population humaine est associée à un risque de mortalité augmenté et à une suceptibilité accrue à certains types de maladies.

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