Methods of preparing a foam comprising a sclerosing agent

Details Methods of preparing a foam comprising a sclerosing agent Methods of preparing a foam comprising a sclerosing agent

A - Human Necessities

61

K

A61K 9/12 (2006.01) A61M 5/155 (2006.01) A61M 5/19 (2006.01) A61P 9/14 (2006.01)

Patent

CA 2546227

A therapeutic foam for the treatment of, inter alia, varicose veins comprises a sclerosing solution foamed with a physiological gas such as carbon dioxide, oxygen or a mixture thereof. The foam has a nitrogen content of less than 0.8%. It may be generated using a pressurised canister system incorporating a fine mesh of micron dimensions through which the gas and sclerosing liquid are passed to make the foam. Alternativelt, the foam may be generated by passing gas and solution between two syringes through a fine mesh. Techniques are described for minimising the amount of nitrogen in a canister or syringe based product. A technique for generating and delivering foam simultaneously using a syringe based device is also disclosed.

Cette invention concerne une mousse thérapeutique servant au traitement, entre autres choses, des veines variqueuses, qui comprend une solution sclérosante en mousse avec un gaz physiologique tel que du dioxyde de carbone, de l'oxygène ou un mélanges desdits gaz. Cette mousse à une teneur en azote inférieure à 0.8%. Elle peut être obtenue au moyen d'un système de cartouche sous pression dans laquelle est intégrée un mince treillis de dimensions microcoques que traversent le gaz et l'agent sclérosant avant de se transformer en mousse. En variante, la mousse peut être produite par le passage d'un gaz et d'une solution entres deux seringues via un mince treillis. Sont décrites des techniques propres à minimiser le volume d'azote dans une cartouche ou dans une seringue. L'invention concerne également une technique de production et d'administration simultanées de mousse au moyen d'un dispositif à seringue.

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