Methods of preparing primary, secondary and tertiary...

Details Methods of preparing primary, secondary and tertiary... Methods of preparing primary, secondary and tertiary...

C - Chemistry, Metallurgy

07

C

C07C 209/24 (2006.01) C07C 209/88 (2006.01)

Patent

CA 2682366

The present application relates to novel methods for the preparation of primary, secondary and tertiary carbinamine compounds, particularly the preparation of compounds of formulae I, IV and VI, from a carbonyl compound of formula II in the presence of ammonia or an ammonium equivalent of the formula NH4 +X-, by way of allylation, crotylation, arylation, reductive amination and catalytic hydrogenation.

La présente invention concerne de nouveaux procédés de préparation de composés carbinamide primaires, secondaires et tertiaires, en particulier la préparation de composés représentés par les formules I, IV, et VI, à partir d'un composé carbonyle représenté par la formule II en présence d'ammoniac ou d'un équivalent ammonium représenté par la formule NH4 +X-, au moyen d'une allylation, d'une crotylation, d'une arylation, d'une amination réductive et d'une hydrogénation catalytique.

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