A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/498 (2006.01) A61P 25/00 (2006.01)
Patent
CA 2530487
The present invention provides a method of preventing or reducing the severity of a stress-associated condition in a subject by systematically administering to the subject an effective amount of brimonidine or a pharmaceutically acceptable salt, ester, amide, stereoisomer or racemic mixture thereof. Stress-associated conditions that can be treated according to a method of the invention include, but are not limited to, dyspepsia, tachycardias other than tachycardia associated with myocardial ischemia, panic attack, non-inflammatory dermatological conditions, disorders of muscle contraction, sensory hypersensitivity associated with migraine, and behavioral disorders.
La présente invention concerne une méthode destinée à prévenir ou atténuer la gravité d'un état associé au stress chez un sujet. La méthode consiste à administrer de façon systémique au sujet une quantité efficace de brimonidine ou un sel pharmaceutiquement acceptable, un ester, un amide, un stéréoisomère ou leur mélange racémique. Des états associés au stress pouvant être traités selon la méthode de l'invention comprennent, mais pas exclusivement, la dyspepsie, les tachycardies autres que celles associées à l'ischémie myocardique, la crise de panique, les états dermatologiques non inflammatoires, les troubles de la contraction musculaire, l'hypersensibilité sensorielle associée à la migraine, et les troubles du comportement.
Brin Mitchell F.
Donello John E.
Gil Daniel W.
Whitcup Scott M.
Allergan Inc.
Gowling Lafleur Henderson Llp
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