A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/395 (2006.01) C07K 16/24 (2006.01) C07K 16/28 (2006.01)
Patent
CA 2439852
The present invention provides to methods of preventing, treating or ameliorating one or more symptoms associated with an autoimmune or inflammatory disorder utilizing combinatorial therapy. In particular, the present invention provides methods of preventing, treating, or ameliorating one or more symptoms associated with an autoimmune or inflammatory disorder comprising administering to a subject in need thereof one or more integrin .alpha.V.beta.3 antagonists and at least one other prophylactic or therapeutic agent. The present invention also provides compositions and articles of manufacture for use in preventing, treating or ameliorating one or more symptoms associated with an autoimmune or inflammatory disorder.
L'invention concerne des méthodes de prévention, d'amélioration ou de traitement d'un ou de plusieurs symptômes associés à un trouble auto-immun ou inflammatoire, reposant sur une thérapie combinatoire. Plus particulièrement, l'invention concerne des méthodes de prévention, d'amélioration ou de traitement d'un ou de plusieurs symptômes associés à un trouble auto-immun ou inflammatoire, consistant à administrer au sujet atteint un ou plusieurs antagonistes de l'intégrine .alpha.¿V?.beta.¿3,? en association avec au moins un agent prophylactique ou thérapeutique. Par ailleurs, l'invention concerne des compositions et des articles de préparation utilisés pour prévenir, traiter ou améliorer un ou plusieurs symptômes associés à un trouble auto-immun ou inflammatoire.
Dingivan Christine
Wilder Ronald
Medimmune Inc.
Osler Hoskin & Harcourt Llp
LandOfFree
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